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The monkeypox vaccine with independent intellectual property rights in China was approved for clinical use. On December 10th, the monkeypox vaccine jointly developed by China Bio-Beijing Institute of Biological Products and China Center for Disease Control and Prevention received the approval notice of drug clinical trial issued by National Medical Products Administration, and it was registered and classified as Class 1.2 innovative vaccine. The vaccine is an innovative vaccine independently developed by scientists in China with completely independent intellectual property rights, which is expected to play an important role in the prevention and control of diseases caused by monkeypox virus in China. (China Biology)In the latest centralized purchase of sitagliptin tablets, the price dropped to less than 20 cents per tablet, with a drop of over 90%. The reporter learned at the scene of the tenth batch of drug centralized purchase that more than 30 companies bid for sitagliptin, which is known as the largest variety in this centralized purchase, including Huahai Pharmaceutical, Kelun Pharmaceutical, Zhengda Tianqing, tonghua dongbao, Zhejiang Pharmaceutical, Jiudian Pharmaceutical, Shiyao Ouyi, Chenxin Pharmaceutical and many other companies. Judging from the bidding results, the lowest bid price among enterprises has dropped below 0.2 yuan per piece, which is more than 90% lower than the limit price. Statistics show that in 2023, the sales of this product in the terminals of public medical institutions in China exceeded 2 billion yuan, and the sales of Merck, the original research manufacturer, accounted for more than 90%, so there is a large room for generic drug substitution. The quotation of Meradong in this collection is about 7.37 yuan per piece. (science and technology innovation board Daily)Market information: The major shareholders of Hershey, an American chocolate manufacturer, will reject the takeover proposal of Yizi International, thinking that the other party's offer is too low.

Adobe's US stocks fell about 9% before the market, and the company's annual performance guidance was worse than expected.The Environmental Protection Department of the National Development and Reform Commission organized the liaison meeting of the coordination mechanism of cleaner production promotion departments in 2024. On the afternoon of December 10th, the Environmental Protection Department of the National Development and Reform Commission organized the liaison meeting of the coordination mechanism of cleaner production promotion departments in 2024 to sort out and summarize the latest progress, existing problems and difficulties in the implementation of cleaner production in 2024, study the key tasks in 2025, and promote the completion of the objectives and tasks of the Tenth Five-Year Plan.IEA monthly report: global oil inventories rebounded in November. OECD crude oil inventories fell by 30.9 million barrels in October. It was observed that global oil inventories fell by 39.3 million barrels in October.

Zelensky's office stated that it was ready to negotiate with Russia. Mikhail Podolyak, adviser to the director of Ukrainian President Zelensky's office, said in an interview with Channel 24 that Kiev was ready to negotiate with Russia. He pointed out that simple solutions should not be expected, and Ukraine needs just peace conditions. Earlier, Kremlin spokesman dmitry Peskov said that Russia was willing to negotiate with Ukraine provided that the conditions proposed by Russian President Vladimir Putin were met. The conditions mentioned include the complete withdrawal of Ukrainian troops from new Russian regions and Ukraine's neutrality.Dashengda and Tuopai Shede Group set up investment partnerships. According to the enterprise search APP, Sichuan Fujiang Yingke Investment Partnership (Limited Partnership) was recently established with a capital contribution of 200 million yuan. Its business scope includes: asset management services invested by its own funds; Enterprise management consulting; Information technology consulting service. Enterprise equity penetration shows that the enterprise is jointly held by Dashengda and Sichuan Tuopai Shede Group Co., Ltd..The full implementation of the personal pension system may bring more medium and long-term funds, and the allocation value of the Southern Shanghai and Shenzhen 300ETF(159925) has attracted much attention. On December 12, the Southern Shanghai and Shenzhen 300ETF(159925) closed up 1.07%, with a turnover of 92.5438 million yuan. The constituent stocks were all red, with Contemporary Amperex Technology Co., Limited rising by 2.47%, Kweichow Moutai rising by 1.97% and Wuliangye rising by 1.62%. China Merchants Bank and China Ping An followed suit. In the news, since December 15th, the personal pension system has been extended to the whole country, and the first batch of 85 index funds have been included in the product range, which has attracted attention, including 12 Shanghai and Shenzhen 300 index funds and 300ETF(159925) in South China. According to industry insiders, since the personal pension fund system came into being, both personal pension funds and sales organizations have steadily expanded. The increase of fund products and the continuous addition of new sales organizations will bring more medium and long-term funds to the capital market, and the Southern CSI 300ETF(159925) will benefit in the medium and long term.